Oncology

19 Jan 2023

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Triple Negative Breast Cancer: What Medical Files to Collect For Your Case To Be Reviewed Within 3 Days

In-Clinic & Distance Treatment for Patients Outside of Latvia

If you’ve been cancer clean after chemo, radio, or surgery, but then the disease returned, most likely you are searching for an alternative treatment.

But before we go into details, there’s one thing you should know about triple negative breast cancer treatment using Rigvir in Latvia. And it’s this - if you’d like to qualify for Rigvir® therapy, start collecting your medical files TODAY (or simply fill out the short form on the right or click the submit inquiry button to send your inquiry for a free case evaluation so the patient coordinator will contact you within 24 hours).

Knowing that collecting medical records can be time-consuming for you, the medical team will email you normally during the first 48-72 hours. And if you get approved for Rigvir® therapy, the team will immediately offer you the Rigvir therapy based on your health condition.

Here’s the same list of medical files in case you need to copy/paste it:

  • biopsy (or pathology report)
  • lab tests
  • cytology report
  • PET/CT/MRI scan results
  • etc.

What To Know Before Qualifying For Triple Negative Breast Cancer Rigvir Treatment in Latvia

  1. Painlessness: it is a standard intramuscular injections.
  2. The selectiveness of action: as already mentioned, only cancer cells are Rigvir® targets. Rigvir® cannot reproduce itself in a human body outside the cancer cell.
  3. The flexibility of use: even if you’ve already been treated with surgery and/or radiation, you can still try Rigvir® injections or combine the injections with other standard cancer treatment including surgery and chemotherapy.
  4. No side effects: radio and surgery also treat melanoma skin cancer, but a lot of patients then face hair loss and pain after radiation, while Rigvir® doesn’t cause them. Because Rigvir® leaves healthy cells untouched, it has shown little or no side effects. Specifically, the body temperature may rise up to 99.5 °F/37.5 °C and stay such for up to three days.

Rigvir can be delivered to your doorstep no matter where you live

Rigvir affects malignant cells only

In general, Rigvir® seeks and infects malignant cells inside your body. It then quickly replicates inside the cells and stays laser-focused on their destruction. Because cancer cells usually camouflage themselves as healthy ones, Rigvir® unveils their mask and mobilizes your entire immune system to fight the disease.

Sometimes it is hard to imagine this process, you can watch this short video-explainer:

Success Rates Of Rigvir® Therapy In Numbers

Rigvir® isn’t a magic pill. Not even close to it.

And if we stick to dry facts, officially the drug improves the survival rates in melanoma patients only. However, real-life experience shows there’s much more to it than just treating melanoma. Here’s what you should know about the success rates of Rigvir® since 1960’s until today.

Rigvir reduces viability of breast cancer cell cultures [1]

Rigvir has also been used in other types of cancer. In vitro, it reduces the viability of melanoma, as well as pulmonary, gastric, pancreatic, bone, and breast cancer cell cultures. It is oncolytic in melanoma and rectum cancer patients and has been shown to improve the 5-year survival in rectum cancer patients.

It was found that Ad5F11bSP-Rantes has strong infectivity and effective killing activity against breast cancer cells [2]

In the established triple negative breast cancer (TNBC) xenograft model in NCG mice whose immune system was humanized with human peripheral blood mononuclear cells (PBMCs), Ad5F11bSP-Rantes achieved 88.33% tumor inhibition rate. Rantes expression was high in mouse blood, a large number of CD3+ lymphocytes infiltrated in tumor tissues and E-cadherin was up-regulated in cancer cells, suggesting that Ad5F11bSP-Rantes altered the TME and induced a reversal of cancer cell epithelial–mesenchymal transition (EMT). In conclusion, oncolytic adenovirus can exert the oncolytic effect and the chemotactic effect of immune cells and realize the synergy of multiple anticancer effects. This strategy creates a candidate treatment for the optimization of breast cancer, especially TNBC, combination therapy.

Enteroviruses effect in eight of the nine breast cancer cell lines investigated [3]

Breast cancer cells were also shown to be sensitive to Coxsackievirus A21. High multiplicity viral infection produced a rapid cytopathic effect in eight of the nine breast cancer cell lines investigated, while no cytopathic action was observed in the control cell line of normal breast cells.

Our clinic has already helped 1218 patients to win over cancer (including breast cancer patients)

As Rigvir is quite new means of cancer treatment (it was registered in approved in 2004), not so many clinics throughout the world offer it.

You may find ones outside Latvia (European Union). Wherever you are, time is not your friend now and it is not a good option to get treatment where doctors are just gaining experience in using Rigvir.

The best option to win over cancer is to visit the destination that is a proven world leader in Rigvir® treatment and has already helped more than 1218 patients (including 38 breast cancer patients).

In 2011 Rigvir was added to the list of state reimbursed drugs approved by the National Health Service of Latvia. This allows all Latvian patients diagnosed with malignant melanoma to use Rigvir at no cost. In 2015 and 2016 the drug was approved by the national registration authorities in Georgia and Armenia accordingly.

In 2016, Rigvir producing company received funding from the European Commission program “Horizon 2020” taking one more step forward to be registered in Europe.

To date, Latvia remains the world’s teaching hub offering in-depth Rigvir training courses, certification, and accreditation of cancer clinics in the field.

Special offer to foreign patients: treatment plan from €3900 ($4100) instead of €4500 ($4750)

melanoma treatment clinicskin cancer ClinicAmber Life Cancer ClinicAmber Life Cancer Clinicmelanoma alternative treatment
 
 

Nadine (UK) with metastasized malignant melanoma since 1999:

“...I can still play with my children”*

*Results may vary

Jane from the US with with ocular melanoma:

“...I chose not to do the conventional therapy in the United States…And the doctor that did my blood test in the United States was astounded, he couldn’t believe it, he hadn’t seen that...”*

*Results may vary

4 Things to Keep in Mind Before Qualifying for Rigvir® Therapy

  • You must be 18 years old or older as there is no evidence that Rigvir® treats pediatric cancer.
  • Your tumor must be solid as Rigvir® doesn't treat blood cancers such as leukemia, lymphoma, or myeloma.
  • Your tumor must be malignant as Rigvir® treats cancer cases only.
  • Your purpose must be treatment other than prevention as Rigvir® cannot be applied as a preventive measure.

You can apply virotherapy as a monotherapy or combine it with chemo and radio. If you still have doubts or want to learn whether you or someone can benefit from the treatment, click the button below to submit your inquiry.


List of References

  1. “Adapted ECHO-7 Virus RigVir Immunotherapy (oncolytic Virotherapy) Prolongs Survival in Melanoma Patients after Surgical Excision of the Tumour in a Retrospective Study.” - Doniņa, Simona; Strēle, Ieva; Proboka, Guna; Auziņš, Jurgis; Alberts, Pēteris; Jonsson, Björn; Venskus, Dite; Muceniece, Aina. Melanoma Research: October 2015 - Volume 25 - Issue 5 - p 421–426. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4560272/
  2. “Chimeric Oncolytic Adenovirus Armed Chemokine Rantes for Treatment of Breast Cancer" - Lin Ang, Jiang Li, Hui Dong, Chunhong Wang, Jin Huang, Mingcong Li, Min Zhao, Changqing Suand Qiang Wu https://mdpi-res.com/d_attachment/bioengineering/bioengineering-09-00342/article_deploy/bioengineering-09-00342-v2.pdf?version=1658888160
  3. "Oncolytic Enteroviruses" - P. M. Chumakov, V. V. Morozova, I. V. Babkin, I. K. Baikov, S. V. Netesov, and N. V. Tikunova. Molecular Biology, 2012, Vol. 46, No. 5, pp. 639–650. © Pleiades Publishing, Inc., 2012. https://www.virotherapy.com/publications/preclinical/oncolytic-enteroviruses-2012.pdf